ARA-290

Identity

Field	Value
IUPAC name	(4S)-5-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-oxo-4-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoic acid
SMILES	C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCC(=O)N1
InChI	InChI=1S/C51H84N16O21/c1-22(2)17-30(47(84)65-32(19-36(53)71)48(85)66-33(20-68)49(86)67-34(21-69)50(87)88)63-40(77)24(5)57-41(78)25(7-6-16-56-51(54)55)59-43(80)29(11-15-39(75)76)62-46(83)31(18-23(3)4)64-45(82)27(8-12-35(52)70)60-44(81)28(10-14-38(73)74)61-42(79)26-9-13-37(72)58-26/h22-34,68-69H,6-21H2,1-5H3,(H2,52,70)(H2,53,71)(H,57,78)(H,58,72)(H,59,80)(H,60,81)(H,61,79)(H,62,83)(H,63,77)(H,64,82)(H,65,84)(H,66,85)(H,67,86)(H,73,74)(H,75,76)(H,87,88)(H4,54,55,56)/t24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-/m0/s1
InChIKey	WZTIQQBMSJTRBR-WYKNNRPVSA-N

Chemistry

Field	Value
Compound class	Undecapeptide (11 aa, EPO-derived)
Formula	C₅₁H₈₄N₁₆O₂₁
Molecular weight	1257.3
CAS	1208243-50-8
PubChem	PubChem CID 91810664 (opens in a new tab)

2D structure

PubChem 2D depiction · CID 91810664

3D structure

Computed conformer: one plausible shape of a flexible molecule, not a measured structure · RDKit

Additional properties

Computed
Property	Value
Exact mass	1256.59969375 Da
Monoisotopic mass	1256.59969375 Da
XLogP3	-7.7
Topological polar surface area	623 Å²
Hydrogen bond donors	20
Hydrogen bond acceptors	22
Rotatable bonds	42
Heavy atoms	88

Also known as

Cibinetide, PHBSP, pHBSP peptide, Cibinetida, Pglu-glu-gln-leu-glu-arg-ala-leu-asn-ser-ser, pyroglutamate helix B surface peptide, Pyr-glu-gln-leu-glu-arg-ala-leu-asn-ser-ser-OH, UEQLERALNSS

Identifiers

Registry identifiers
Registry	Value
UNII	9W5677JKDA (opens in a new tab)
DSSTox	DTXSID701384981 (opens in a new tab)
DrugBank	DB13006 (opens in a new tab)
Wikidata	Q27273306 (opens in a new tab)

Sources

Data sources
Source	Kind	Retrieved
Computed conformer (RDKit ETKDGv3 + MMFF94)	Internal	Oct 12, 2026
PubChem CID 91810664 (opens in a new tab)	PubChem	Oct 12, 2026

Products containing this compound

Listed products
Product	Milligrams
ARA-290	entire fill